A Prospective Comparison of the 30-Minute and 60-Minute Oxytocin Dose Incremental Schedules for Induction of Labor at Term

  • Idowu P Ade-Oju, Oluwafemi Kuti, Olabisi Loto, Solomon O Ogunniyi


Aim: To compare the efficacy and safety of two oxytocin incremental protocols used for induction of labor in women of low parity.

Method: One hundred and twenty women (120) of low parity requiring induction of labour at term were randomly assigned into the two oxytocin induction dose protocols of the 30-minute and 60-minute incremental intervals. Induction–onset of labour interval, Induction-delivery interval, Delivery outcome and perinatal outcome were compared.

Results: The induction-onset of labour interval and the induction delivery interval were comparable between the 60-min group and the 30-min group. Intrapartum complications like fetal distress, uterine hyperstimulation and precipitate labour were more common in the 30-min group however, this was not statistically significant.

Conclusion: Oxytocin infusion regimens of 60-min and 30-min are comparable in outcome for induction of labour. The 60-min group carries less risk to both the mother and the fetus.

Keywords: Induction-delivery interval, Induction of labor, oxytocin

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