Pregnancy Outcome In Hypertensive Disorder Of Pregnancy With Low Platelet count

Abstract

Aims: To study pregnancy outcome in HDP with low platelet count.

Objectives: This study aimed to assess the frequency of occurrence, identify diverse delivery methods, and investigate the maternal and fetal outcomes associated with Hypertensive Disorders of Pregnancy (HDP) in the presence of low platelet count.

Methodology: This cross-sectional descriptive study took place at Paropakar Maternity and Women’s Hospital (PMWH) in Kathmandu, focusing on hospital-based data. The sample size was 35. Total duration of data collection was 6 months from shrawan 2078 to poush 2078.

Results: A total of 35 cases fulfilling the inclusion criteria were enrolled. Incidence of HDP with low platelet count was 100/810 (12.3%). Majority of cases were primigravida 19/35(54.3%), of age group 20-24 10/35(28.6%). Mostly, pre-eclampsia cases had thrombocytopenia 17/35(48.5%). Majority of cases 21/35 (60%) had LSCS and 14/35 (40 %) had vaginal delivery. Maternal complication included MICU admission, HELLP syndrome, PPH and abruptio placenta and fetal complication were LBW, NICU admission, Perinatal asphyxia, IUFD, IUGR and early NND were noted.

Conclusions: This study reveals a significant association between HDP accompanied by thrombocytopenia and heightened maternal and fetal morbidity. The primary
maternal complications observed included admission to the Maternal Intensive Care Unit (MICU) for monitoring post the administration of a loading dose of MgSo4, followed by occurrences of HELLP syndrome and PPH. Fetal complications encompassed admissions to the NICU, instances of LBW, perinatal asphyxia, IUGR, and IUFD.