Serum β-hCG Levels between 13-20 Weeks Gestation can Predict Development of Pregnancy Induced Hypertension

  • G Kour Combined Hospital, Sikandrabad, Uttar Pradesh, India
  • S Kour 2 Department of Obstetrics and Gynecology Acharaya Sri Chander College of Medical Sciences, Sidhra, Jammu, Jammu & kashmir India

Abstract

Aims: To find out predictive value of serum β human chorionic gonadotropin (β HCG) levels between 13-20 weeks of gestation in predicting the development of pregnancy induced hypertension (PIH) or pre-eclampsia, eclampsia.


Methods: Serum β HCG level was estimated in 200 normotensive patients between 13-20 weeks of gestation. The median value of Serum β HCG was calculated and patients were divided into two groups as per two times multiple of median (2MOM) values of Serum β HCG i.e. those above and below the 2MOM values. The patients were followed up to delivery and were evaluated for the development of PIH, pre-eclampsia and eclampsia.


Results: As per the median score of Serum β HCG in studied patients, the determined value of 2MOM was 30845 mIU/ml. Out of 200 patients, 23 (11.5%) patients were found to have values of Serum β HCG ≥ 2MOM. Twelve (52%) patients in Serum β HCG ≥ 2MOM group developed hypertension on follow up as compared to 13 (7.3%) patients in < 2MOM group (p< 0.0001). Also patients in the ≥ 2MOM group had higher prevalence of maternal and fetal complications.


Conclusions: Serum β HCG levels between 13-20 weeks of gestation can predict development of PIH in pregnant females


Keywords: β HCG; maternal complications; pregnancy-induced hypertension

Published
Jan 3, 2019
How to Cite
KOUR, G; KOUR, S. Serum β-hCG Levels between 13-20 Weeks Gestation can Predict Development of Pregnancy Induced Hypertension. Nepal Journal of Obstetrics and Gynaecology, [S.l.], v. 13, n. 1, p. 12-14, jan. 2019. ISSN 1999-8546. Available at: <http://njog.org.np/njog/index.php/njog/article/view/925>. Date accessed: 24 mar. 2019.
Section
Original Articles