Identification and Antimicrobial Susceptibility Pattern of Clinically Significant Coagulase-negative Staphylococci

  • A Nazir, A Shah, D Kakru, S M Kadri

Abstract

Aims: This study was undertaken to determine the prevalence and pathogenicity of coagulase-negative staphylococci in clinical samples and to study the antibiotic-sensitivity pattern of the coagulase-negative isolates.

Methods: A prospective study was conducted over a period of two years on patients admitted in the Sher-i-Kashmir Institute of Medical Sciences. Blood, urine, pus, catheter tips, cerebrospinal fluid and peritoneal fluid samples of patients who fulfilled the criteria for being labeled as nosocomial were cultured.

Results: One hundred and six strains of coagulase negative staphylococci were isolated from the samples and among them 90 isolates were identified as Staphylococcus epidermidis (84.90%). Most of the coagulase-negative staphylococci isolates were resistant to penicillin, cephalosporins and fluoroquinolones. Methicillin resistance was found in a significant number of coagulase-negative isolates. All the isolates were found to be sensitive to vancomycin.

Conclusions:  The results of the study emphasized that isolation of coagulase-negative staphylococci should be viewed with serious concern and accurate species identification and antimicrobial susceptibility testing should be performed in all cases.

How to Cite
D KAKRU, S M KADRI, A Nazir, A Shah,. Identification and Antimicrobial Susceptibility Pattern of Clinically Significant Coagulase-negative Staphylococci. Nepal Journal of Obstetrics and Gynaecology, [S.l.], v. 9, n. 2, p. 73-78, aug. 2015. ISSN 1999-8546. Available at: <http://njog.org.np/njog/index.php/njog/article/view/57>. Date accessed: 13 july 2020.
Section
Brief Communication